PIPages
Labs

Rachel Solnick

Icahn School of Medicine at Mount Sinai, NY·Medicine & Clinical Research·Early-career

Emergency departments (EDs) see many people at higher risk of HIV, including patients diagnosed with sexually transmitted infections (STIs). These visits are an underused chance to start HIV pre-exposure prophylaxis (PrEP), a medication taken to prevent HIV infection and a key part of the National HIV/AIDS Strategy.

Fields

Medicine & Clinical Research

Public Health & Epidemiology

Topics

HIV prevention

pre-exposure prophylaxis

PrEP

Grants
1 known grant, through Apr 2029

What they work on

  1. Develop the TIPPED protocol, which uses routine post-discharge callbacks about STI results to offer HIV pre-exposure prophylaxis (PrEP), together with an implementation strategy shaped by stakeholder input.
  2. Adapt a Persuasive Health Communication Intervention (PHCI), a tailored counseling message, that emergency department clinicians can deliver during their regular callbacks to encourage patients to start PrEP.
  3. Test whether the PHCI message increases PrEP initiation and adherence among STI-diagnosed patients discharged from the emergency department, using a nested pilot randomized controlled trial.
  4. Evaluate TIPPED's feasibility, fidelity and acceptability in practice, and measure PrEP initiation and linkage to care using interrupted time-series analysis of electronic health record data.

More about the research

The research asks how EDs can start these patients on PrEP and then connect them to ongoing outpatient care.

Why it matters

People diagnosed with an STI in an emergency department are at higher risk of HIV, yet many leave without HIV prevention care. A workable phone-based way to start PrEP after discharge could expand HIV prevention for this group. It could also improve PrEP initiation, linkage to outpatient care and adherence. If it works, the protocol could be tested and adopted across many emergency departments.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Telephone Initiated PrEP Post-ED Discharge (TIPPED)

NIH · May 2024 – Apr 2029

Closest labs

Madeline Renny

Icahn School of Medicine at Mount Sinai, NY·Medicine & Clinical Research·Early-career

Adapt an evidence-based brief negotiated interview and change plan for youth at higher risk of a substance use disorder in the pediatric emergency department, using the ADAPT-ITT framework, a stakeholder board and youth pilot testing.

Anne Fehrenbacher

University of Southern California, CA·Public Health & Epidemiology·Early-career

Model barriers and facilitators for adopting a digital PrEP implementation strategy within India's National AIDS Control Organization Targeted Intervention programs, guided by the EPIS implementation science framework.

Dovie Watson

University of Pennsylvania, PA·Public Health & Epidemiology·Early-career

Identify changeable provider-, practice-, and community-level factors that affect PrEP delivery in primary care, using the Consolidated Framework for Implementation Research (CFIR), a structured list of factors that shape program adoption.

The school

Icahn School of Medicine at Mount Sinai: 45 labs on PI Pages, $1.0B a year on research, 62 research doctorates a year.

More about Icahn School of Medicine at Mount Sinai

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