PIPages
Labs

Jennifer Clarke

University of California-San Francisco, CA·Medicine & Clinical Research

Clinical trials test new cancer treatments in patients, and each trial has to be scientifically sound, practical to run, and worth the patients' and staff's effort. A cancer center running many trials at once needs a way to judge which studies are well designed, which can realistically enroll enough patients, and which should come first.

Fields

Medicine & Clinical Research

Public Health & Epidemiology

Topics

clinical trials

cancer clinical research

protocol review

Grants
1 known grant, through May 2028

What they work on

  1. Run disease- and discipline-focused site committees that give each proposed cancer clinical trial a first scientific review, judge its feasibility and expected enrollment, and set its priority.
  2. Review the scientific rationale, design, statistical support and expected enrollment of every clinical study through the center-wide Protocol Review and Monitoring Committee, and track ongoing studies for progress and accrual.
  3. Rank all clinical research studies across the cancer center to match its strategic plan, giving priority to the local cancer burden, high-priority cancers, and underserved or marginalized communities.

More about the research

This grant supports that oversight system at the Helen Diller Family Comprehensive Cancer Center (HDFCCC) at UCSF.

Why it matters

Careful review and monitoring of cancer clinical trials helps make sure the trials a cancer center runs are well designed, can enroll enough patients to answer their questions, and focus on the cancers that matter most for its region. Giving priority to studies on high-burden cancers and underserved or marginalized communities could help direct trial resources toward patients who have historically had less access to clinical research.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Protocol Review and Monitoring System

NIH · Aug 1999 – May 2028

Closest labs

Lawrence Flaherty

Wayne State University, MI·Medicine & Clinical Research

Conduct a two-stage scientific review of cancer clinical trial protocols, first by multidisciplinary disease teams and then by the Protocol Review and Monitoring Committee, judging rationale, design, statistics and feasibility.

Andrew Armstrong

Duke University, NC·Medicine & Clinical Research

Conduct a two-stage scientific review of all proposed cancer-related studies at the Duke Cancer Institute, covering study merit, feasibility, impact and fit for the relevant patient population before ethics board review.

Martha Mims

Baylor College of Medicine, TX·Medicine & Clinical Research

Support cancer clinical trials across the Dan L Duncan Comprehensive Cancer Center by providing protocol development, financial and regulatory oversight, research nursing and data management through the Clinical Trials Support Unit.

The school

University of California-San Francisco: 89 labs on PI Pages, $2.1B a year on research, 164 research doctorates a year.

More about University of California-San Francisco

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