Lawrence Flaherty
Wayne State University, MI·Medicine & Clinical Research
Clinical trials in cancer need careful vetting before they open and steady monitoring once they start. Without this, studies may duplicate each other, compete for the same patients, or stall before they finish.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
- Topics
cancer clinical trials
protocol review
clinical trial monitoring
- Grants
- 1 known grant, through Nov 2026
What they work on
- Conduct a two-stage scientific review of cancer clinical trial protocols, first by multidisciplinary disease teams and then by the Protocol Review and Monitoring Committee, judging rationale, design, statistics and feasibility.
- Prioritize protocols across the cancer center to avoid duplicate studies and trials that compete for the same patients, considering fit with open trials and expected enrollment.
- Regularly monitor patient enrollment in open clinical trials so that studies stay on track to meet their scientific aims within the planned timeframes.
More about the research
This grant supports the Protocol Review and Monitoring System (PRMS) at the Karmanos Cancer Institute (KCI). The system reviews the scientific merit of every clinical research protocol involving cancer patients. It also sets priorities among protocols across the cancer center and tracks their progress.
Why it matters
Careful scientific review and enrollment tracking help cancer trials at the Karmanos Cancer Institute be well designed, avoid redundancy, and finish on time. This could help patients with cancer get access to trials that are more likely to answer their research questions. It may also make better use of clinical resources across the center.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Jennifer Clarke
University of California-San Francisco, CA·Medicine & Clinical Research
Run disease- and discipline-focused site committees that give each proposed cancer clinical trial a first scientific review, judge its feasibility and expected enrollment, and set its priority.
Andrew Armstrong
Duke University, NC·Medicine & Clinical Research
Conduct a two-stage scientific review of all proposed cancer-related studies at the Duke Cancer Institute, covering study merit, feasibility, impact and fit for the relevant patient population before ethics board review.
Martha Mims
Baylor College of Medicine, TX·Medicine & Clinical Research
Support cancer clinical trials across the Dan L Duncan Comprehensive Cancer Center by providing protocol development, financial and regulatory oversight, research nursing and data management through the Clinical Trials Support Unit.
The school
Wayne State University: 21 labs on PI Pages, $292M a year on research, 194 research doctorates a year.
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