Michael Garrett
University of Southern Mississippi, MS·Biochemistry
Modern biomedical research often relies on expensive instruments and specialized skills, for example to read all the genes active in a single cell or to edit a gene. Many researchers in Mississippi, especially at undergraduate colleges, could not afford these tools on their own.
- Fields
Biochemistry
Genetics
Biology
- Topics
core facility
shared instrumentation
multiomics
- Grants
- 1 known grant, through Aug 2028
What they work on
- Provide Mississippi INBRE investigators with consultation and technical services in multiomics, CRISPR/Cas9 gene editing, bioenergetic cell assays and imaging through five shared core facilities.
- Add new high-throughput methods to the core, including single-cell RNA sequencing, which reads gene activity cell by cell, and spatial transcriptomics, which maps gene activity within tissue.
- Train students and faculty at Mississippi institutions to use genomics, proteomics, metabolomics, gene editing and imaging technologies.
- Improve existing assays and acquire new instruments to keep the shared core facilities current and sustainable.
More about the research
This project runs a shared Instrumentation and Services Core (ISC) for the Mississippi IDeA Network of Biomedical Research Excellence (INBRE). The core gives investigators across the state access to advanced technology and to expert help using it.
Why it matters
By giving Mississippi researchers, particularly at undergraduate institutions, access to sequencing, gene editing, proteomics, metabolomics and imaging, the core could help them study the molecular basis of biomedically important processes. This would otherwise be out of reach for these researchers. It also trains students and faculty in these technologies, building the state's biomedical research capacity.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Toren Finkel
University of Pittsburgh, PA·Biology
Build a high-resolution map of senescent cells, cells that stop dividing permanently, in human lung and heart, using single-cell RNA and ATAC sequencing, proteomics and spatial transcriptomics.
James Papin
University of Oklahoma-Health Sciences Center, OK·Biochemistry
Provide next-generation DNA and RNA sequencing, and bioinformatics analysis of combined genomic, proteomic and metabolomic data, to cancer center members and other investigators.
Jian Ouyang
Medical University of South Carolina, SC·Genetics
Provide reliable, cost-effective next-generation sequencing library preparation, including bulk RNA-seq, ChIP-seq, ATAC-seq and methylation sequencing, for cancer center investigators.
The school
University of Southern Mississippi: 3 labs on PI Pages, $94M a year on research, 362 research doctorates a year.
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