James Papin
University of Oklahoma-Health Sciences Center, OK·Biochemistry
Cancer research today depends on costly instruments and specialized expertise: machines that read DNA, instruments that identify thousands of proteins, cell sorters, microscopes and computer pipelines that combine many types of data. Most individual labs cannot afford or run all of these.
- Fields
Biochemistry
Genetics
Medicine & Clinical Research
- Topics
core facility
shared resource
next-generation sequencing
- Grants
- 1 known grant, through Apr 2028
What they work on
- Provide next-generation DNA and RNA sequencing, and bioinformatics analysis of combined genomic, proteomic and metabolomic data, to cancer center members and other investigators.
- Offer protein identification and analysis of chemical modifications using liquid chromatography with tandem mass spectrometry (nano LC/MS/MS), plus metabolite and small-molecule measurements in the newer Mass Spectrometry Core.
- Support flow cytometry, microscopy and high-throughput live-cell screens of cancer cells, including gene copy number, metabolic analysis and colony-forming (clonogenic) assays, along with training and help with experimental design.
More about the research
This grant supports a shared central facility that gives cancer researchers across a campus access to these tools, along with help designing experiments and interpreting results.
Why it matters
Shared access to sequencing, proteomics, metabolomics, cytometry and bioinformatics lets many cancer research groups make measurements they could not make alone. This supports work on how cancer cells grow, signal and use energy. By training users and helping with study design and analysis, the facility could improve the quality and reach of cancer studies across the campus.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Drew Jones
New York University, NY·Biochemistry
Provide metabolomics services to cancer researchers, including global and untargeted metabolomics, lipidomics, mass spectrometry imaging and custom targeted methods for measuring specific metabolites.
Xiang Zhang
University of Louisville, KY·Biochemistry
Support hepatobiology and toxicology research projects with established omics technologies, providing metabolomic, proteomic, lipidomic and bioinformatic analyses of investigator samples.
Zoran Galic
University of California-Los Angeles, CA·Medicine & Clinical Research
Provide cancer center investigators with flow cytometry, mass cytometry, imaging cytometry and cell sorting services using instruments such as the Helios mass cytometer, ImageStream imaging cytometer and Aria high-speed sorters.
The school
University of Oklahoma-Health Sciences Center: 11 labs on PI Pages, $474M a year on research, 31 research doctorates a year.
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