Larry Jackson
Duke University, NC·Medicine & Clinical Research·Early-career
Atrial fibrillation is an irregular heart rhythm that raises the risk of stroke. Blood-thinning drugs called oral anticoagulants (OAC) lower that risk.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
- Topics
atrial fibrillation
oral anticoagulants
stroke prevention
- Grants
- 1 known grant, through Dec 2026
What they work on
- Interview Black and White patients with non-valvular atrial fibrillation and their clinicians to identify barriers to and facilitators of shared decision making about oral anticoagulants, the blood thinners that prevent stroke.
- Develop a patient decision support tool that explains the risks and benefits of oral anticoagulants, and refine it through repeated rounds of evaluation with patients and clinicians.
- Run a pilot study to test whether the decision support tool is feasible and acceptable for supporting shared decision making among Black patients with atrial fibrillation, preparing for a future randomized trial.
More about the research
Yet Black patients with non-valvular atrial fibrillation (NVAF), the form not caused by heart valve disease, are less likely than White patients to receive these drugs, even though they face about three times the risk of NVAF-related stroke. Black patients are also more likely to be left out of decisions about their own care. This project asks whether helping patients and clinicians make the choice together, known as shared decision making, can narrow this gap.
Why it matters
Black patients with atrial fibrillation face a higher risk of stroke and death but are less likely to receive stroke-preventing blood thinners. A decision support tool that improves shared decision making could help these patients make informed, values-based choices, may raise anticoagulant use, and could reduce racial disparities in heart rhythm care.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Laura Cabrera Trujillo
Pennsylvania State University, PA·Medicine & Clinical Research
Identify neuroethical concerns and decision-making needs about early versus late use of advanced neurotechnology, using interviews and validated instruments with patients, caregivers and clinicians.
Fenan Rassu
Johns Hopkins University, MD·Medicine & Clinical Research·Early-career
Measure how socioeconomic status affects use of pain psychology among patients with chronic low back pain, using a retrospective analysis of data from a multi-site trial in Baltimore and Salt Lake City.
Anna Pfenniger
Northwestern University, IL·Medicine & Clinical Research·Early-career
Map when and where endothelial dysfunction appears during atrial fibrillation, especially the shift from paroxysmal to persistent AF, in two large animal models of AF.
The school
Duke University: 61 labs on PI Pages, $1.6B a year on research, 417 research doctorates a year.
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