Paula Aristizabal
University of California-San Diego, CA·Medicine & Clinical Research
Children who join cancer clinical trials tend to survive at higher rates, yet Hispanic children with cancer join these trials far less often than non-Hispanic White children. This gap matters because Hispanic children have higher rates of several cancers and worse overall survival.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
- Topics
childhood cancer
pediatric oncology
Hispanic health
- Grants
- 1 known grant, through Jun 2028
What they work on
- Test whether COMPRENDO, a program in which trained parent peers give culturally and linguistically matched education during informed consent, increases enrollment of Hispanic children in therapeutic cancer trials compared with consent from the oncologist alone.
- Measure whether COMPRENDO improves parents' understanding of informed consent and their voluntariness (agreeing to research without feeling pressured), using a multisite randomized clinical trial.
- Assess COMPRENDO's effects on parents' decisional regret, confidence in making decisions, and satisfaction with the consent process.
- Explore the factors that help or hinder putting COMPRENDO into practice at four sites with diverse Hispanic populations, to guide wider scale-up.
More about the research
By 2030 they will also make up about a third of U.S. children. The team's earlier data point to one barrier: limited research literacy, meaning a family's capacity to understand research information and act on it when deciding whether to take part.
Why it matters
Hispanic children with cancer are underrepresented in clinical trials, which limits their access to new therapies and to the survival benefit linked to trial enrollment. If peer navigation proves effective across sites, it could become a reproducible way to raise trial participation among Hispanic families. It could also help make sure new cancer treatments are tested in, and benefit, Hispanic patients of all ages.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Jaime Peterson
Oregon Health & Science University, OR·Medicine & Clinical Research
Test whether Kinder Coaching, a parent coaching program delivered by community health workers, improves preschoolers' school readiness on the Brigance III screen compared with a provider-reviewed checklist, in a randomized trial of 240 Medicaid families in Oregon.
Scott Halpern
University of Pennsylvania, PA·Medicine & Clinical Research·Early-career
Test whether mobile patient recruitment strategies make enrollment in respiratory failure randomized trials more representative of the patients who would later receive the treatments.
Alice Carter
University of Massachusetts-Boston, MA·Psychology
Test in a randomized trial across 20 Early Intervention agencies whether training providers in Reciprocal Imitation Training (a play-based therapy) improves language and social communication in toddlers with early autism signs, compared with usual care.
The school
University of California-San Diego: 84 labs on PI Pages, $1.9B a year on research, 637 research doctorates a year.
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