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Samuel Urlacher

Baylor University, TX·Social Science

Children burn about 50% more calories per day than adults, relative to body size. That high energy use may come at a hidden cost.

Fields

Social Science

Physiology

Public Health & Epidemiology

Topics

oxidative stress

free radicals

antioxidants

Grants
1 known grant, through Jul 2027

What they work on

  1. Measure total energy expenditure in children aged 3–10 using doubly labeled water, a method that tracks harmless isotope-tagged water to calculate daily calorie use.
  2. Quantify oxidative stress in the same children with an oxidative stress index that weighs urinary 8-OHdG, a DNA damage marker, against antioxidant activity.
  3. Test how children's daily energy expenditure relates to oxidative stress as a life history trade-off, adding household food and nutrition data to the bioassay results.

More about the research

Burning energy produces free radicals, reactive molecules that can damage cells. When free radicals outpace the body's antioxidant defenses, the result is oxidative stress, which is linked to chronic disease and higher mortality. Antioxidant defenses also cost energy, and in childhood that energy could otherwise go to growth. This doctoral dissertation project asks how children balance these demands. It frames the question as a life history trade-off: competing uses of a limited energy budget.

Why it matters

Learning how energy use links to cellular damage in childhood could guide public health priorities and disease prevention. Families and child health programs could gain clearer insight into how energy demands, nutrition and antioxidant defenses interact during growth. This could matter for preventing chronic conditions tied to oxidative stress.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Doctoral Dissertation Research: The energetic cost of cellular oxidative stress in children

NSF · Aug 2025 – Jul 2027

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The school

Baylor University: 5 labs on PI Pages, $135M a year on research, 280 research doctorates a year.

More about Baylor University

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