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Vivian Go

University of North Carolina at Chapel Hill, NC·Public Health & Epidemiology

Heavy drinking can make it harder for people to take the medicines that prevent or control HIV. Treating unhealthy alcohol use, which ranges from risky drinking to alcohol use disorder, could therefore help stop new infections.

Fields

Public Health & Epidemiology

Medicine & Clinical Research

Topics

HIV prevention

pre-exposure prophylaxis

PrEP

Grants
2 known grants, through Jul 2027

What they work on

  1. Test whether the brief alcohol intervention (BAI), counseling based on Motivational Interviewing and Cognitive Behavioral Therapy, improves PrEP persistence and adherence in a randomized trial of 564 PrEP users with unhealthy drinking in Hanoi, Vietnam.
  2. Measure the BAI's effect on heavy drinking days and other alcohol outcomes among PrEP users, using timeline followback interviews and alcohol biomarkers.
  3. Estimate the cost per quality-adjusted life-year gained, feasibility and acceptability of scaling up the BAI in PrEP clinics throughout Vietnam.
  4. Compare facilitation alone with an experiential approach, where staff receive the BAI themselves first, for BAI delivery fidelity and patient viral suppression in a cluster-randomized trial of 30 antiretroviral therapy clinics in Vietnam.
  5. Use mixed methods to identify clinic and staff traits behind successful BAI scale-up and measure how experiencing the BAI changes staff members' own alcohol attitudes and use.

More about the research

Both projects test a short counseling program, the brief alcohol intervention (BAI), in Vietnam. One tests whether it helps people taking HIV-prevention pills; the other tests how best to roll it out in HIV clinics nationwide. The BAI draws on Motivational Interviewing and Cognitive Behavioral Therapy and has already been shown to increase viral suppression in people with HIV.

Why it matters

Unhealthy alcohol use is common among people with HIV and people taking PrEP, and it undermines the medicines that suppress or prevent HIV. If the brief alcohol intervention improves PrEP use and viral suppression, these trials could guide rapid scale-up in Vietnamese clinics and inform how U.S. HIV clinics treat unhealthy drinking, including through clinician continuing education.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

A brief alcohol intervention to reduce alcohol use and improve PrEP outcomes: A randomized controlled trial.

NIH · Sep 2022 – Jul 2027

Scaling up the brief alcohol intervention to prevent HIV infection in Vietnam: a cluster randomized, implementation trial

NIH · Sep 2022 – Jul 2027

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The school

University of North Carolina at Chapel Hill: 72 labs on PI Pages, $1.6B a year on research, 523 research doctorates a year.

More about University of North Carolina at Chapel Hill

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