Jennifer Koblinski
Virginia Commonwealth University, VA·Medicine & Clinical Research
Cancer research often relies on tumor models that do not reflect the full range of patients a hospital actually treats. If the models used to study tumors and test drugs come mostly from a narrow group of patients, findings may not apply equally well to everyone.
- Fields
Medicine & Clinical Research
Biology
- Topics
patient-derived xenograft
cancer models
tumor models
- Grants
- 1 known grant, through Jun 2028
What they work on
- Develop more than 500 new patient-derived xenograft (PDX) models, patient tumors grown in mice, from the patient populations served by the cancer center.
- Characterize the new PDX models so that researchers know the features of each tumor they study.
- Test the PDX models so they can support cancer center research studies that better represent the center's patient population.
More about the research
This project aims to build a large, more representative collection of living tumor models.
Why it matters
Tumor models that come from a broad cross-section of a cancer center's patients could help ensure that research findings and drug testing apply to the people the center actually treats, including groups that may be underrepresented in existing models. A collection of more than 500 new patient-derived xenografts could serve as a shared resource for cancer studies at the center.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Moon Chen
University of California-Davis, CA·Public Health & Epidemiology
Administer internal pilot projects within the University of California-UT Southwestern Diversity Patient-Derived Xenograft Development and Trial Center, focused on gastric and lung tumor models from Latino, African American, and Asian American/Native Hawaiian/Pacific Islander patients.
Anna Malovannaya
Baylor College of Medicine, TX·Biochemistry
Provide antibody-based protein profiling for cancer researchers using a custom reverse phase protein array (RPPA), which measures many specific proteins across many samples.
Hernan Flores-Rozas
Florida Agricultural and Mechanical University, FL·Medicine & Clinical Research
Expand the center's physical and virtual biorepositories into a single access point for diverse, well-annotated tumor specimens from Florida and California patient populations.
The school
Virginia Commonwealth University: 19 labs on PI Pages, $524M a year on research, 438 research doctorates a year.
Reach out
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