PIPages
Labs

Hernan Flores-Rozas

Florida Agricultural and Mechanical University, FL·Medicine & Clinical Research

Cancer research depends on access to real patient tissue, but well-documented samples are scarce for the populations that carry a higher cancer burden. This core facility serves the Florida-California Cancer Research, Education and Engagement (CaRE2) Health Center.

Fields

Medicine & Clinical Research

Pharmacology

Public Health & Epidemiology

Topics

cancer

biorepository

biobank

Grants
1 known grant, through Aug 2028

What they work on

  1. Expand the center's physical and virtual biorepositories into a single access point for diverse, well-annotated tumor specimens from Florida and California patient populations.
  2. Acquire living tumor tissue and develop patient-derived xenografts, human tumors grown in mice, to speed drug development and test how drug response varies with patient background.
  3. Supply pancreatic and prostate cancer tissue blocks and plasma and serum samples to the CaRE2 center's research projects, and transfer drug-development methods to FAMU.

More about the research

It builds and shares a collection of preserved and living tumor tissues so that the center's investigators can study cancer differences across patient groups and develop new drugs.

Why it matters

Many patient groups with a higher cancer burden are underrepresented in tissue banks and genomic data. Expanding biospecimen collections and patient-derived tumor models from these groups could help researchers learn why cancers such as pancreatic and prostate cancer differ between populations. It could also help test drugs on tumors that better reflect the patients who need them.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Tissue Modeling and Drug Discovery Core

NIH · Sep 2018 – Aug 2028

Closest labs

Diana Wilkie

University of Florida, FL·Medicine & Clinical Research

Investigate the biological basis of differences in pancreas cancer outcomes among Florida and California populations, using specimens collected across the three-institution partnership in a full project and a pilot project.

Ileana Mauldin

University of Virginia, VA·Medicine & Clinical Research

Provide cancer researchers with animal models of cancer and human-derived materials, along with expert help in planning, running and analyzing studies of investigational diagnostic and therapeutic agents.

Jennifer Koblinski

Virginia Commonwealth University, VA·Medicine & Clinical Research

Develop more than 500 new patient-derived xenograft (PDX) models, patient tumors grown in mice, from the patient populations served by the cancer center.

The school

Florida Agricultural and Mechanical University: 5 labs on PI Pages, $69M a year on research, 41 research doctorates a year.

More about Florida Agricultural and Mechanical University

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