PIPages
Labs

Erin Hecht

Harvard University, MA·Neuroscience·Early-career

How does evolution reshape the brain to produce new behaviors? Some species, and some breeds within a species, seem built to learn particular skills or to behave in particular ways.

Fields

Neuroscience

Ecology & Evolution

Psychology

Topics

comparative neuroscience

brain evolution

reactive aggression

Grants
2 known grants, through Feb 2028

What they work on

  1. Relate reactive aggression to gray matter shape, white matter microstructure and connectivity in chimpanzees, using existing MRI and DTI scans paired with behavioral measures from the same animals.
  2. Collect validated reactive and proactive aggression measures and matching brain scans in humans, then compare human, chimpanzee and bonobo brains to test for evolved changes in aggression circuits.
  3. Compare ape and human brain organization with patterns found in tame foxes to independently test whether humans and bonobos were selected for reduced reactive aggression.
  4. Identify brain features linked to breed-specific predispositions for learned skills, such as herding or scent detection, using MRI, diffusion and resting-state imaging of 220 dogs from 4 breeds.
  5. Separate brain plasticity from learning skills in a dog's lifetime from inherited breed differences, and find brain markers that predict working-dog performance ratings.

More about the research

A leading theory also proposes that humans, like bonobos, were selected for reduced impulsive aggression. The lab tests these ideas by comparing brain scans with behavior, both within species and across them, using structural brain imaging of apes, humans and dogs.

Why it matters

Understanding whether humans evolved reduced reactive aggression, and which brain circuits support it, adds to knowledge of what makes our species distinct. Brain markers of real-world working skill in dogs could help organizations that breed and train guide, service and scent-detection dogs. The open datasets and analysis tools will be available to other researchers.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

CAREER: Integrating brain-behavior evolution with real-world science impacts through neuroscience of working dogs

NSF · Mar 2023 – Feb 2028

Evolved changes to neural systems for reactive aggression in humans and other primates

NSF · Jul 2023 – Jun 2027

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Yasmin Zakiniaeiz

Yale University, CT·Neuroscience·Early-career

Measure baseline dopamine D2/3 receptor levels in the prefrontal cortex of men and women with alcohol use disorder and sex-matched controls, using PET imaging with the radiotracer [11C]FLB457.

Ying-Hui Chou

University of Arizona, AZ·Neuroscience

Determine whether excitatory or inhibitory rTMS, magnetic pulses delivered through the scalp and aimed at the hippocampus, improves memory more than sham stimulation, in a randomized crossover trial of 60 adults with amnestic mild cognitive impairment.

The school

Harvard University: 42 labs on PI Pages, $1.5B a year on research, 712 research doctorates a year.

More about Harvard University

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