Elias Klemperer
University of Vermont, VT·Public Health & Epidemiology
Cigarette smoking is still the leading cause of preventable illness and death in the United States. A growing number of smokers also use e-cigarettes, and these "dual users" often keep smoking for years.
- Fields
Public Health & Epidemiology
Psychology
Medicine & Clinical Research
- Topics
tobacco regulatory science
smoking
cigarettes
- Grants
- 1 known grant, through Dec 2028
What they work on
- Test whether very low nicotine content cigarettes reduce cigarettes smoked per day and cigarette dependence among adult dual users of cigarettes and e-cigarettes, in a 12-week double-blind randomized trial.
- Determine whether access to high-nicotine versus low-nicotine e-cigarettes changes the effect of very low nicotine cigarettes on smoking, using a 2 x 2 factorial design.
- Measure exposure to tobacco toxicants among dual users across cigarette and e-cigarette nicotine conditions to assess health-related effects of nicotine product standards.
More about the research
The U.S. Food and Drug Administration plans to cap nicotine in cigarettes at a level low enough to be minimally or non-addictive. Meanwhile, policymakers have proposed limiting e-cigarette nicotine to 2% or less to curb youth vaping. Earlier trials of very low nicotine content (VLNC) cigarettes showed that smokers cut back, but those trials left out regular e-cigarette users. So it is unclear how these two policies would work together.
Why it matters
Results could give the FDA direct evidence on how a cap on cigarette nicotine would affect the large group of adults who both smoke and vape. They could also show whether limiting e-cigarette nicotine would weaken that policy's benefits. This evidence could help regulators set tobacco product standards that reduce smoking and toxic exposure.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Meghan Morean
Yale University, CT·Public Health & Epidemiology
Refine an ENDS nicotine concentration label so its strength categories are anchored to cigarette nicotine content, using expert feedback and focus groups.
Jason D Robinson
University of Texas MD Anderson Cancer Center, TX·Medicine & Clinical Research
Compare quit rates after six weeks of varenicline versus dual nicotine replacement therapy (patch plus lozenge) among 2,000 Texas smokers in a virtually delivered SMART trial, confirming abstinence by breath carbon monoxide.
Michael Kotlyar
University of Minnesota, MN·Public Health & Epidemiology
Test whether people who smoke menthol cigarettes take up nicotine pouches more than medicinal nicotine, using a randomized 6-week study of 252 participants in an experimental marketplace.
The school
University of Vermont: 16 labs on PI Pages, $246M a year on research, 76 research doctorates a year.
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