Lauren B Krupp
New York University, NY·Medicine & Clinical Research
Multiple sclerosis (MS) is the most common disabling disease of the brain and spinal cord in young adults. Its burden falls unevenly: Black, Hispanic and poverty-affected communities often fare worse.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
- Topics
multiple sclerosis
childhood adversity
adverse childhood experiences
- Grants
- 1 known grant, through Nov 2029
What they work on
- Develop culturally sensitive research instruments for measuring childhood adversity, together with people with multiple sclerosis from Black, Hispanic and poverty-affected communities and community engagement partners.
- Analyze how individual, family and neighborhood-level childhood adversity relates to MS health outcomes in a multicenter cohort made up mostly of people from high-risk groups.
- Identify environmental and social factors influencing quality of life in minority and poverty-affected people with MS, to find modifiable targets for a clinical trial across the U.S. Network of MS Centers.
More about the research
This project asks whether hardship in childhood helps explain these gaps. It examines adversity experienced at the level of the individual, the family and the neighborhood.
Why it matters
Black, Hispanic and low-income people with multiple sclerosis often face worse health outcomes. By pinpointing how childhood adversity and social conditions relate to MS outcomes, this work could identify modifiable factors. These could become the basis for tailored, community-based interventions and a multicenter clinical trial aimed at improving health and quality of life.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Nancy L Monson
University of Texas Southwestern Medical Center, TX·Microbiology & Immunology
Test whether plasmablasts, antibody-secreting cells derived from B cells and expanded in African American and Hispanic patients with multiple sclerosis, make antibodies that bind to neurons.
Robert Turner
Duke University, NC·Neuroscience
Test whether repetitive head impacts and traumatic brain injury from American football are linked to worse later-life memory, thinking and psychiatric symptoms in Black male former players compared with unexposed Black men.
Audrey Pettifor
University of North Carolina at Chapel Hill, NC·Public Health & Epidemiology
Test whether the longitudinal link between childhood adversity and depression differs by cash transfer exposure, using HPTN 068 trial data on 2,533 rural South African girls and Child Support Grant data from the Agincourt surveillance system.
The school
New York University: 72 labs on PI Pages, $1.5B a year on research, 540 research doctorates a year.
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