Lisa Rong
Weill Medical College of Cornell University, NY·Medicine & Clinical Research·Early-career
Coronary artery disease, the narrowing of arteries that feed the heart, is a leading cause of illness and death. It is often treated with coronary artery bypass grafting (CABG), surgery that reroutes blood around blockages using blood vessels taken from elsewhere in the body.
- Fields
Medicine & Clinical Research
Physiology
- Topics
coronary artery disease
coronary artery bypass grafting
multiple arterial grafting
- Grants
- 1 known grant, through May 2027
What they work on
- Compare how single versus multiple arterial grafting during bypass surgery changes heart function, measured as echo strain by transesophageal echocardiography, and whether changes relate to blood pressure-support drug use.
- Test whether reduced blood flow to the heart muscle, measured with contrast-enhanced echo and a flowmeter, explains post-surgery strain declines and whether it is lower after multiple arterial grafting.
- Determine whether the post-surgery drop in echo strain predicts patients' clinical outcomes at 6 months better than conventional heart imaging measures.
More about the research
Surgeons can use a single arterial graft (SAG) or multiple arterial grafts (MAG). Arterial grafts stay open longer than vein grafts, but patients receiving MAG may face higher risk around the time of surgery. How each approach affects heart function right after surgery, and what that means for recovery, is not well understood.
Why it matters
Patients having bypass surgery for coronary artery disease could benefit if heart imaging during surgery reveals who is likely to have poor heart function afterward. Linking grafting strategy, blood flow and heart muscle strain could guide anesthesia and medication choices around surgery, and later tests of drugs that improve graft flow, with the goal of better recovery.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Ethan Tumarkin
University of Utah, UT·Biomedical Engineering
Design and build a trans-nasal transesophageal echocardiography prototype that passes an ultrasound probe through the nasal orifice to image the heart from the esophagus without sedation.
Malamo Countouris
University of Pittsburgh, PA·Medicine & Clinical Research·Early-career
Test in a randomized trial whether an angiotensin receptor blocker-neprilysin inhibitor (ARNI) lowers left ventricular mass index more than an angiotensin receptor blocker alone in women with prior preeclampsia and current hypertension.
Theodore Abraham
University of California-San Francisco, CA·Medicine & Clinical Research
Determine how heart muscle function limits exercise in non-obstructive HCM by measuring regional and global myocardial strain with echocardiography at rest and at peak exercise, and relating it to exercise capacity.
The school
Weill Medical College of Cornell University: 35 labs on PI Pages, $1.6B a year on research, 59 research doctorates a year.
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