PIPages
Labs

Ying Fang

University of Illinois Urbana-Champaign, IL·Microbiology & Immunology

SARS-CoV-2, the virus behind COVID-19, can infect animals as well as people. Domestic cats, tigers and lions are highly susceptible, as earlier work by this team and others showed.

Fields

Microbiology & Immunology

Medicine & Clinical Research

Public Health & Epidemiology

Topics

SARS-CoV-2

coronavirus

zoonosis

Grants
1 known grant, last ended Aug 2026

What they work on

  1. Generate and characterize SARS-CoV-2-specific antibody reagents and diagnostic standards for COVID-19 research and diagnostics.
  2. Develop rapid assays to detect SARS-CoV-2 infection in any animal species, including a serological DIVA test that tells vaccinated animals apart from infected ones.
  3. Establish a feline model of SARS-CoV-2 infection to study how the virus causes disease and how the host immune system responds.
  4. Apply the new assays to surveillance of pets and zoo animals to identify animal reservoirs of SARS-CoV-2 and inform models of infection risk.

More about the research

When the virus passes back and forth between humans and animals, it may pick up new mutations, and animals could become hidden reservoirs. Tracking the virus in animals requires tests that work across species and a good animal model of the disease.

Why it matters

Animals that carry SARS-CoV-2 could pass it back to people or drive new viral variants. Tests that work across species could help find animal reservoirs and protect veterinarians, zoo staff and pet owners. A feline model could also serve as a tool for screening vaccine and drug candidates.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Novel diagnostic tools and animal model system for study human/animal interface of COVID-19

NIH · Sep 2021 – Aug 2026

Closest labs

Pamela Wong

University of Michigan, MI·Microbiology & Immunology

Profile the immune responses raised by the combined nanoemulsion plus RIG-I-agonist adjuvant paired with multiple SARS-CoV-2 antigens, comparing injection and mucosal routes, to identify optimal formulations and delivery.

Marco Salemi

University of Florida, FL·Public Health & Epidemiology

Test whether SARS-CoV-2 evolves faster within immunocompromised people with HIV by using phylodynamic analysis, which reconstructs viral family trees from genetic sequences, to track variants that arise inside one person.

Fuqing Wu

University of Texas Health Science Center at Houston, TX·Public Health & Epidemiology

Build models that connect how virus levels change inside one infected person with how the virus passes between people, so that SARS-CoV-2 levels in wastewater can be read as measures of community transmission.

The school

University of Illinois Urbana-Champaign: 41 labs on PI Pages, $907M a year on research, 870 research doctorates a year.

More about University of Illinois Urbana-Champaign

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