PIPages
Labs

Sreekalyani Bhamidi

University of North Carolina at Chapel Hill, NC·Mathematics & Statistics

Networks are everywhere in modern data: how information and misinformation spread through social media, how brain regions connect, how genes influence one another. Researchers increasingly feed network representations into multi-step machine learning pipelines and draw scientific conclusions from the output.

Fields

Mathematics & Statistics

Computer Science

Topics

network analysis

multilayer networks

functional data analysis

Grants
1 known grant, through Aug 2028

What they work on

  1. Develop statistically principled methods for summarizing, clustering, and extracting principal directions of variation in multilayer network data, using Gaussian process optimal transport and Procrustes metrics on covariance operators expressed via Wasserstein distance.
  2. Analyze optimal-transport methods for time registration and supervised learning in evolving complex systems, motivated by single-cell RNA-seq developmental trajectories and network neuroscience, including clustering after quotienting out the trajectory.
  3. Study thresholding pipelines applied to covariance and correlation matrices in Gaussian graphical models through local weak convergence to limiting infinite structures, and derive implications for how thresholds should be selected.
  4. Connect hierarchical representation learning to continuum scaling limits via the relationship between linkage clustering and thresholding, for high-dimensional data with a latent network linking features.
  5. Characterize penalized estimation and limiting distributions of random adjacency matrices, including eigenvector localization, and use these results for hub detection in gene-expression data from cancer genomics.

More about the research

What is often missing is a theory telling us whether those conclusions are reliable. This project builds the mathematical foundations for two widely used families of network and high-dimensional methods, so users can know what the methods actually estimate and how accurate they are.

Why it matters

Conclusions about brain connectivity, cell development, and gene interaction networks increasingly rest on network and graphical-model pipelines whose statistical accuracy is unverified. Theory on convergence, thresholding choices, and hub detection would let analysts in neuroscience, single-cell biology, and cancer genomics choose tuning parameters defensibly and know when an apparent structure in their data is real rather than an artifact of the method.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

NSF-SNSF: Functional data analysis for complex systems

NSF · Sep 2024 – Aug 2028

Closest labs

Marianna Pensky

University of Central Florida, FL·Mathematics & Statistics

Extend the multiplex Generalized Dot Product Graph model so that groups of network layers can have different underlying structures. This would allow layers to be clustered by condition.

Joshua Cape

University of Wisconsin-Madison, WI·Mathematics & Statistics·Early-career

Develop nonparametric spectral clustering and dimension-reduction methods that tolerate messy, mixed data, and apply them to brain network studies of schizophrenia with psychiatry collaborators.

Adrian Lewis

Cornell University, NY·Mathematics & Statistics

Extend Łojasiewicz-type rescaling techniques to analyze the complexity of first-order and active-set algorithms on semi-algebraic problems in hyperbolic, non-Euclidean and infinite-dimensional spaces.

The school

University of North Carolina at Chapel Hill: 72 labs on PI Pages, $1.6B a year on research, 523 research doctorates a year.

More about University of North Carolina at Chapel Hill

Reach out

A start for your email. Fill in the brackets.