PIPages
Labs

Matthew Banks

University of Wisconsin-Madison, WI·Neuroscience

What changes in the brain when we lose consciousness under anesthesia, fall into dreamless sleep, or become delirious? Finding reliable signatures of these states is central to understanding consciousness itself.

Fields

Neuroscience

Medicine & Clinical Research

Psychology

Topics

consciousness

general anesthesia

sleep

Grants
1 known grant, through Apr 2027

What they work on

  1. Identify intracranial EEG biomarkers that distinguish conscious and unconscious states while epilepsy patients go under and emerge from general anesthesia.
  2. Determine biomarkers that separate unconsciousness from waking, drowsiness, and dreaming across sleep stages, using cortical responses to unexpected sounds and speech and cortical connectivity patterns.
  3. Use these biomarkers, together with electrical stimulation and computational modeling of rapid network changes, to study delirium in neurosurgical patients after surgery and seizures.

More about the research

It would also help doctors monitor patients who cannot report their own awareness. This project starts from the idea that brain markers of altered arousal and awareness share common features, whatever condition causes them.

Why it matters

Reliable brain markers of consciousness could lead to better algorithms for monitoring the depth of anesthesia. They could also improve diagnosis, management, and prognosis for patients with central sleep disorders, delirium, vegetative or minimally conscious states, and coma.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Mechanisms of Loss, Recovery and Disorders of Consciousness

NIH · Feb 2014 – Apr 2027

Closest labs

Sharona Ben-Haim

University of California-San Diego, CA·Neuroscience·Early-career

Test whether self-reported post-surgical pain is linked to reduced beta-band activity in the prefrontal cortex, and whether opioid pain relief reverses it, using intracranial EEG in epilepsy-monitoring patients.

Nishant Sinha

University of Pennsylvania, PA·Biomedical Engineering·Early-career

Build scalable pipelines that automatically aggregate and jointly analyze structural MRI, intracranial EEG (IEEG) and clinical data from multiple epilepsy centers, so analyses generalize across sites.

Richard M Leahy

University of Southern California, CA·Neuroscience

Develop Brainstorm tools for experiments that use naturalistic, non-repeating stimuli, including machine- and human-readable labels for uncontrolled events and behavior, so these can be linked to recorded brain activity.

The school

University of Wisconsin-Madison: 91 labs on PI Pages, $1.9B a year on research, 854 research doctorates a year.

More about University of Wisconsin-Madison

Reach out

A start for your email. Fill in the brackets.