Robin Harris
Arizona State University Campus Immersion, AZ·Biology
When cells die, they release signals that tell surviving neighbors how to respond, whether to survive, divide or rebuild. Most of what is known comes from apoptosis, a tidy, programmed form of cell death.
- Fields
Biology
Genetics
- Topics
necrosis
apoptosis
NiA
- Grants
- 1 known grant, through Jul 2027
What they work on
- Identify how necrosis in the Drosophila wing imaginal disc triggers necrosis-induced apoptosis (NiA), cell death far from the wound, using a genetic tool that induces necrosis and manipulates surrounding cells.
- Determine how necrosis-induced apoptosis drives the regenerative cell division needed for wing disc recovery after necrotic injury.
- Characterize the full genetic program of necrosis-induced regeneration in fly wing discs using whole-genome sequencing approaches, and compare it with regeneration after apoptosis.
More about the research
Necrosis is different: it is rapid, disordered cell death. It occurs in burns, frostbite, infections, strokes and heart attacks. Whether necrotic cells also send signals that help or hinder repair is largely unknown, and the answer could shape how necrotic wounds are treated.
Why it matters
Necrosis contributes to tissue damage in burns, frostbite, infections, strokes and heart attacks. Identifying the genes and signals that let tissue recover after necrosis could point to ways to improve healing of necrotic wounds and encourage regeneration in patients.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Kenneth Irvine
Rutgers University-New Brunswick, NJ·Biology
Determine how phase-separated condensates of Warts with Jub, and Jub-promoted phosphorylation of the Warts N-terminus, inhibit this Hippo pathway kinase in Drosophila tissues.
Jin Jiang
University of Texas Southwestern Medical Center, TX·Biology
Determine how different levels or durations of Hedgehog signal produce different outcomes inside cells, combining genetics, biochemistry, biophysics and cell biology in Drosophila and mammalian cells.
Bryce LaFoya
University of Wisconsin-Madison, WI·Biology·Early-career
Screen neural stem cells in Drosophila and zebrafish for proliferation regulators that become polarized, or concentrated on one side, in the mother cell before asymmetric division, using live imaging of developing brains.
The school
Arizona State University Campus Immersion: 36 labs on PI Pages, $1.0B a year on research, 625 research doctorates a year.
Reach out
A start for your email. Fill in the brackets.