PIPages
Labs

Catherine Sun

University of California-San Francisco, CA·Medicine & Clinical Research·Early-career

Diabetes can damage the blood vessels of the retina, the light-sensing tissue at the back of the eye. This diabetic retinopathy is the leading cause of preventable blindness among working-age adults in the United States.

Fields

Medicine & Clinical Research

Public Health & Epidemiology

Computer Science

Topics

ophthalmology

diabetic retinopathy

diabetes

Grants
1 known grant, through May 2027

What they work on

  1. Develop an automated method to identify patients with proliferative diabetic retinopathy in electronic health records, combining structured data such as diagnosis codes, medications and labs with unstructured clinical notes.
  2. Predict progression from non-proliferative diabetic retinopathy to the proliferative form using a forecasting model with time-varying covariates in the UCSF De-Identified Clinical Data Warehouse.
  3. Determine the real-world effectiveness of treatments for proliferative diabetic retinopathy using the nationwide IRIS registry of eye care data.

More about the research

Its advanced form, proliferative diabetic retinopathy (PDR), can cause permanent vision loss. Timely diagnosis and treatment often prevent that loss, but some high-risk patients do not get adequate eye care. Little is known about how PDR treatments perform in everyday practice compared with clinical trials.

Why it matters

People with diabetes are at risk of preventable blindness from proliferative diabetic retinopathy. Automated ways to find these patients in health records, predict who will progress, and compare how treatments work in practice could help clinicians catch disease earlier and choose effective care. The methods could also support future EHR-based studies of other eye diseases.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Real-world outcomes of proliferative diabetic retinopathy

NIH · Jun 2021 – May 2027

Closest labs

Yali Jia

Oregon Health & Science University, OR·Biomedical Engineering

Build a 1-MHz, 120° wide-field, high-resolution OCTA system with GPU real-time processing that captures reliable retinal blood-flow images in a single scan, without stitching images together.

Allison Summers

Oregon Health & Science University, OR·Medicine & Clinical Research

Develop large language model pipelines that extract amblyopia treatment, adherence and visual outcome information from free-text ophthalmology clinical notes, where these concepts are documented inconsistently and not in structured EHR fields.

Jeffrey Jarvik

University of Washington, WA·Medicine & Clinical Research

Improve study design methods for musculoskeletal observational studies and clinical trials, to strengthen confirmatory research on which treatments work.

The school

University of California-San Francisco: 89 labs on PI Pages, $2.1B a year on research, 164 research doctorates a year.

More about University of California-San Francisco

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