PIPages
Labs

Meredith McCormack

Johns Hopkins University, MD·Public Health & Epidemiology

Dirty air indoors and outdoors can harm the lungs, and some groups bear more of that harm than others. Black children in low-income neighborhoods have higher rates of asthma and sleep disordered breathing (SDB), and people living with HIV face faster lung decline as they age.

Fields

Public Health & Epidemiology

Medicine & Clinical Research

Topics

asthma

sleep disordered breathing

sleep quality

Grants
2 known grants, through Jul 2027

What they work on

  1. Determine how bedroom air quality, allergens such as mouse allergen, and microbes such as Staphylococcus aureus relate to objectively measured sleep quality in low-income children with asthma in Baltimore City.
  2. Test whether bedroom environmental exposures are linked to upper-airway inflammation and oxidative stress, and whether poor sleep quality is associated with greater asthma morbidity in these children.
  3. Define how outdoor air pollution (PM2.5 and nitrogen dioxide) and household air pollution affect lung function decline and respiratory illness in people living with HIV versus HIV-negative SHIELD cohort participants.
  4. Test whether HIV raises internal pollutant dose or exaggerates oxidative airway and body-wide responses, using albumin adductome mass spectrometry and examining markers of HIV control.

More about the research

The projects ask how pollution, allergens and microbes contribute to these unequal burdens, using careful home and personal exposure measurements alongside health outcomes.

Why it matters

These studies could show which pollutants in homes and outdoor air drive poor sleep, asthma attacks and lung decline. That evidence could guide home interventions to reduce sleep and asthma disparities among inner-city Black children, and could reveal modifiable risk factors and treatment targets for improving lung health and healthy aging in people living with HIV.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Environmental Determinants of Sleep Disparities and the Consequences for Low Income Children with Asthma

NIH · Aug 2021 – Jul 2027

Study of HIV Infection in the Etiology of Lung Disease (SHIELD) AIR: Air Pollution Impact on Respiratory Health in HIV

NIH · Aug 2020 – Jul 2027

Closest labs

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Test whether the HAPIN LPG stove and fuel intervention, given during pregnancy and the first year of life, has lasting benefits for neurological and physical development in children followed to age 5 in Guatemala, India and Rwanda.

Cande Ananth

Rutgers University-New Brunswick, NJ·Public Health & Epidemiology

Build a linked birth database of about 16 million births in five U.S. states from 2000–2016, assigning each residence daily PM2.5 and its components, nitrogen dioxide, ozone, and weather measures.

The school

Johns Hopkins University: 100 labs on PI Pages, $4.1B a year on research, 622 research doctorates a year.

More about Johns Hopkins University

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