Pierce Boyne
University of Cincinnati, OH·Medicine & Clinical Research
Of the 7 million stroke survivors in the U.S., fewer than 10% can walk fast and far enough for everyday tasks like grocery shopping. Rehabilitation guidelines recommend moderate-intensity aerobic walking exercise.
- Fields
Medicine & Clinical Research
Physiology
- Topics
stroke
high-intensity interval training
aerobic training
- Grants
- 1 known grant, through Jun 2028
What they work on
- Determine whether high-intensity interval walking training or moderate-intensity aerobic training safely produces larger, lasting gains in walking capacity in 156 people with chronic stroke, in a 3-site randomized trial.
- Test whether vigorous training intensity is especially important for stroke survivors with severe gait impairment, comparing their response to HIT versus moderate-intensity training.
- Compare changes in fatigue, aerobic capacity and quality of life with HIT versus moderate-intensity training, using blinded assessments up to 3 months after training ends.
More about the research
However, recent evidence suggests it does little for many people more than 6 months after a stroke, especially those with severe walking impairment. More vigorous training might work better, but neurological impairments make it hard for stroke survivors to reach high intensity.
Why it matters
Many stroke survivors cannot walk well enough for daily life even after rehabilitation. If high-intensity interval training safely yields greater and lasting gains in walking and fitness in less time, it could guide how physical therapists choose exercise intensity. This could especially help patients with severe gait impairment, who have not responded meaningfully to current approaches.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Sherrie Khadanga
University of Vermont, VT·Medicine & Clinical Research
Test in a randomized controlled trial whether high-intensity interval training plus high-intensity resistance training improves peak oxygen uptake (VO2peak) and physical function more than standard moderate cardiac rehabilitation exercise.
Matthew Durand
Medical College of Wisconsin, WI·Physiology
Establish whether the muscle metaboreflex, which raises cardiovascular drive when metabolites accumulate in working muscle, is impaired in the paretic leg of chronic stroke survivors, and relate it to voluntary muscle activation and metabolite levels.
Chris Gregory
Medical University of South Carolina, SC·Medicine & Clinical Research
Compare the effects of combined aerobic exercise and repetitive transcranial magnetic stimulation (rTMS), a noninvasive brain stimulation method, versus either treatment alone on depressive symptoms in people with post-stroke depression.
The school
University of Cincinnati: 18 labs on PI Pages, $740M a year on research, 275 research doctorates a year.
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