R. Chinthrajah
Stanford University, CA·Medicine & Clinical Research
Vaccines and natural infections both train the immune system, but the details of how adults build protection against respiratory viruses are still unclear. The center this core belongs to uses influenza and SARS-CoV-2 (the COVID-19 virus), studied after both vaccination and infection, as models.
- Fields
Medicine & Clinical Research
Microbiology & Immunology
- Topics
human immunology
influenza
SARS-CoV-2
- Grants
- 1 known grant, through Apr 2029
What they work on
- Recruit, enroll, and follow adult volunteers in studies of influenza and SARS-CoV-2 vaccination and infection, obtaining ethics approvals and protecting participants' rights.
- Collect blood samples and clinical data according to each study protocol, and send them with matched de-identified data to the center's immune-monitoring lab and research projects.
- Build and manage a central electronic clinical database with quality controls so projects can compare immune results across studies.
More about the research
It aims to define how the adaptive immune system (antibodies and T cells) and the innate immune system (fast first-line defenses) protect adults against viruses. The center gives particular attention to vulnerable people.
Why it matters
Better knowledge of how vaccines and infections protect adults against influenza and COVID-19 could help improve vaccines and protection for vulnerable people. By supplying carefully collected blood samples and reliable clinical data, the Clinical Core makes it possible to link laboratory immune measurements to real patients' vaccine responses and infection outcomes.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Pamela Wong
University of Michigan, MI·Microbiology & Immunology
Profile the immune responses raised by the combined nanoemulsion plus RIG-I-agonist adjuvant paired with multiple SARS-CoV-2 antigens, comparing injection and mucosal routes, to identify optimal formulations and delivery.
Charles Rinaldo
University of Pittsburgh, PA·Microbiology & Immunology
Measure neutralizing antibody function and B lymphocyte responses after Pfizer or Moderna mRNA COVID-19 vaccination in 200 men and women with HIV and 50 HIV-negative controls from the MWCCS.
The school
Stanford University: 87 labs on PI Pages, $1.6B a year on research, 739 research doctorates a year.
Reach out
A start for your email. Fill in the brackets.