Amit Bandyopadhyay
Washington State University, WA·Biomedical Engineering
Hip replacement (total hip arthroplasty) is among the most successful surgeries, but implants can fail early. The ball, or femoral head, is often made of CoCrMo, a cobalt-chromium-molybdenum alloy.
- Fields
Biomedical Engineering
Materials Science
Engineering
- Topics
total hip arthroplasty
hip replacement
orthopedic implants
- Grants
- 1 known grant, through Jan 2027
What they work on
- Determine how calcium phosphate–reinforced titanium alloy composites form a protective tribofilm that resists combined wear and corrosion, and measure how cells respond to these materials in vitro.
- Determine tribocorrosion mechanisms and tribofilm formation in calcium phosphate–reinforced CoCrMo composites, and test whether they release fewer cobalt and chromium ions than pure CoCrMo.
- Measure in vivo biological responses to 3D-printed titanium or CoCrMo alloys with added calcium phosphate, as candidate materials for hip implant femoral heads and taper joints.
More about the research
It connects to a titanium alloy (Ti6Al4V) stem through a tapered joint called the trunnion. Rubbing, crevice and galvanic corrosion at this joint shed debris and release cobalt and chromium ions. These ions can trigger adverse local tissue reactions, immune responses that damage bone and lead to revision surgery. They can also harm hearing, vision and kidneys. This project asks whether implant metals can be designed to protect themselves from this combined wear and corrosion, called bio-tribocorrosion.
Why it matters
3D-printed calcium phosphate–metal composites could lead to hip implant femoral heads that release little or no cobalt and chromium. This could reduce tissue reactions, bone damage and early revision surgeries for hip replacement patients, and lower the risk of ion-related harm to hearing, vision and kidneys.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Susmita Bose
Washington State University, WA·Biomedical Engineering
Determine how natural medicinal compounds such as curcumin, acemannan and vitamin D3 affect bone-forming activity of 3D-printed porous calcium phosphate and ceramic–polymer scaffolds in cell studies, including the needed doses and release rates.
Steven Kurtz
Drexel University, PA·Biomedical Engineering
Develop and optimize a hybrid additive manufacturing process for carbon-fiber-reinforced polyaryletherketones, combining 3D printing with heat-and-pressure consolidation, using design of experiments.
Yiliang Liao
Iowa State University, IA·Engineering
Determine how the evolving, uneven thermal environment of a hot liquid support bath controls polymer diffusion and interlayer fusion in embedded printing, using deep-neural-network molecular dynamics, phase-field modeling, and experiments.
The school
Washington State University: 22 labs on PI Pages, $403M a year on research, 259 research doctorates a year.
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