PIPages
Labs

Amir Manbachi

Johns Hopkins University, MD·Biomedical Engineering

Hospitalized patients can develop dangerous changes in blood flow, such as deep vein thrombosis (a blood clot in a deep vein), between routine check-ups. Current monitoring often depends on occasional ultrasound exams performed by specialized staff, so problems that arise between exams can be missed.

Fields

Biomedical Engineering

Medicine & Clinical Research

Engineering

Topics

wearable ultrasound

ultrasound patch

deep vein thrombosis

Grants
1 known grant, through Jul 2027

What they work on

  1. Assess, through customer discovery interviews, the clinical need for continuous ultrasound monitoring of blood vessels in hospitalized patients at risk of deep vein thrombosis.
  2. Determine how a wearable ultrasound patch would fit into the workflows of critical care, surgical recovery and vascular health settings, and what barriers could slow its adoption.
  3. Evaluate reimbursement considerations and commercialization pathways for a device that combines a deep-imaging ultrasound transducer with AI-assisted electronic beam steering for automated vessel tracking.

More about the research

Late recognition leads to preventable complications, longer hospital stays and higher costs. This project centers on a wearable ultrasound patch designed to watch blood vessels continuously and flag meaningful changes automatically.

Why it matters

A wearable patch that continuously tracks blood vessels could help clinicians spot deep vein thrombosis and other vascular changes earlier in hospitalized, critically ill and post-surgical patients. That could add to existing clot-prevention strategies, reduce preventable deaths and complications, ease the demand on ultrasound specialists, lower costs, and widen access to DVT monitoring.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

I-Corps: Translation Potential of a Wearable Artificial Intelligence (AI)-Enabled Ultrasound Patch for Deep Vein Thrombosis Detection

NSF · Aug 2026 – Jul 2027

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Julie Jaffray

University of California-San Diego, CA·Medicine & Clinical Research·Early-career

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Congqing Wu

University of Kentucky, KY·Medicine & Clinical Research

Determine how NINJ1 in myeloid immune cells such as macrophages contributes to thrombosis. NINJ1 is the protein that actively ruptures the cell membrane during pyroptosis, an inflammatory form of cell death.

Charles Lowenstein

Johns Hopkins University, MD·Medicine & Clinical Research

Test whether BCOR, a gene-silencing protein, suppresses Factor VII production in liver cells by controlling the epigenetic complexes PRC1.1 and ATAC, which regulate how DNA is packaged and read.

The school

Johns Hopkins University: 100 labs on PI Pages, $4.1B a year on research, 622 research doctorates a year.

More about Johns Hopkins University

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