PIPages
Labs

Tanja Kral

University of Pennsylvania, PA·Public Health & Epidemiology

Children who carry genes linked to obesity do not always become obese. That gap suggests that everyday behaviors may modify inherited risk.

Fields

Public Health & Epidemiology

Medicine & Clinical Research

Psychology

Topics

childhood obesity

pediatric obesity

energy balance

Grants
1 known grant, through Dec 2027

What they work on

  1. Test whether a heightened drive to eat (food reward value, rapid eating and eating without hunger) predicts 1-year changes in weight and body fat in children ages 5 to 7 independently of a genetic risk score or in addition to it.
  2. Identify diet, physical activity and sleep behaviors that may lessen the impact of a high drive to eat or high genetic risk on BMI z-score, percent body fat and waist circumference over one year.
  3. Test whether the protective energy balance behaviors differ for children with a heightened drive to eat compared with children at high genetic risk for obesity.
  4. Examine how family functioning and parent feeding practices shape children's risk-modifying energy balance behaviors in families from low-resource backgrounds.

More about the research

This study asks whether energy balance behaviors, habits of diet, physical activity and sleep, can weaken behavioral and genetic predispositions to obesity in young children. It also asks how families shape those behaviors.

Why it matters

Childhood obesity places a heavy burden on children from low-resource, predominantly minority families. Identifying the diet, activity, sleep and family factors that protect children with a strong drive to eat or high genetic risk could provide new targets for tailored, family-based prevention programs. It could also help reduce health disparities in obesity.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Role of energy balance behaviors in modifying biobehavioral risk factors for childhood obesity

NIH · Mar 2023 – Dec 2027

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Emily Melnick

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Test whether limited neighborhood food access at age 2 predicts less responsive parental feeding practices and less nutritious foods served at ages 3–5, using geocoded data from the ECHO and Care cohorts.

Matthew Haemer

University of Colorado Denver/Anschutz Medical Campus, CO·Public Health & Epidemiology

Compare BMI reduction between the family-inclusive Healthy Living Program and a recommended primary care counseling control in low-income Hispanic children with obesity across three age groups, 2-6, 7-12 and 13-16 years, in a randomized controlled trial.

The school

University of Pennsylvania: 90 labs on PI Pages, $2.2B a year on research, 750 research doctorates a year.

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